DATE OF ADMISSION: 09/12/2011.
CHIEF COMPLAINT: This is a 53-year-old white male seen at the request
of Dr. Ali Rahimtoola for evaluation and treatment of aortic aneurysm
with potential dissection.
HISTORY OF PRESENT ILLNESS: This is a 53-year-old physically active
white male who presents with an essentially asymptomatic type 1 aortic
dissection. The patient begins history by noting a typhus infection in
Maui in 12/2010. From that time, the patient had intermittent episodes
of palpitations and he noted increased pulsations of the abdominal area
since that time. The patient denies inanition, abdominal pain, chest
pain, shortness of breath at any time. He has not had syncope, headache
or any physical disruption from his very active physical activities
including ultimate frisbee, surface boarding, windsurfing and vigorous
mountain biking. The patient biked to the emergency room for a
followup echocardiogram on 09/12/2011 at which time the patient's aortic
insufficiency and aortic aneurysm were noted. The patient on exam
denies any neurologic symptoms, chest pain or shortness of breath. He
has been very active up to the present time. He notes no previous
episodes of chest pain. The patient has had no previous cardiac
history.
PAST
MEDICAL HISTORY: Significant for the absence of diabetes, stroke
or hypertension. He has had previous ACL surgery and has had a duodenal
hematoma from active trauma from an injury at ultimate Frisbee. He did
not require operation.
PHYSICAL EXAMINATION:
GENERAL: This is a tanned and healthy-appearing 53-year-old gentleman
in no distress at rest.
VITAL SIGNS: BP 120/80, heart rate 64, respirations 14, O2 saturation
100 percent on room air.
CHEST: Well-developed.
HEART: Regular rate and rhythm. A brisk systolic and soft diastolic
murmur heard in the aortic position. He has no heaves or lifts.
ABDOMEN: Soft and nontender. Soft palpation is noted at midpoint. He
is definitely without surgical findings of the abdomen.
SKIN: Warm and dry, no lesions seen.
EXTREMITIES: No cyanosis or clubbing. He has equal pulses at the
radial and posterior tibial bilaterally with the Corrigan's pulse.
NEUROLOGIC: Cranial nerves 2-12 grossly intact.
LABORATORY DATA: Echocardiogram from Hood River indicates preserved
left ventricular function, dilated aortic root consistent with aneurysm
and significant aortic insufficiency. A suggestion of dissection is
also present. CT scan carried out at Providence Portland reveals type 1
aortic dissection with greater than 6.5 cm dilatation of the aortic
root. The tear extends all the way down the descending aorta. Both
kidneys have inflow with contrast filling the parenchyma of each kidney.
IMPRESSION AND PLAN: A 53-year-old gentleman with likely chronic aortic
dissection. The extent of the dissection with aneurysmal dilatation
mandates urgent reparative surgery. The patient is a candidate for
aortic replacement with or without aortic root sparing. In addition,
the patient may require a period of circulatory arrest for arch
replacement, stent placement or elephant trunk type repair. The risks
of surgery are high and include paraplegia, stroke, infection, MI,
recurrent dissection and death. This has been discussed with the
patient and his family. They are agreeable to proceed. PARQ was
carried out by myself and also Dr. Eric Kirker who will attend his
surgery. The patient is at extraordinary risk for both medical and
surgical management. It is unusual in that he is largely asymptomatic
from this extensive aortic pathology. Plans for the patient were
discussed with Dr. Cynthia Ferrier who is covering for Dr. Malcolm
Mcaninch today.
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POSTOPERATIVE DIAGNOSIS: Severe aortic insufficiency, type A
dissection, type 1, aortic root arch aneurysm, bicuspid aortic valve.
PROCEDURE: Intravascular ultrasound, thoracic endovascular stent with a
Gore Tag 31 x 15 cm graft for frozen elephant trunk valve-sparing aortic
root replacement (TD5), ascending arch and proximal descending
replacement, also right axillary cannulation and transesophageal
echocardiogram.
ANESTHESIA: General endotracheal anesthesia plus deep hypothermic
circulatory arrest 27 minutes and cardiopulmonary bypass.
SURGEON: Eric Kirker, MD.
ASSISTANT: Kristy Khoury, PA.
INTRAVENOUS FLUID: Not applicable.
ESTIMATED BLOOD LOSS: Not applicable.
SPECIMENS: Ascending and root of aorta were sent.
DRAINS: Blake drain times 2.
COMPLICATIONS: None.
CONDITION: Stable.
DESCRIPTION OF PROCEDURE: The patient taken the operating room and
placed on the table in the supine position. Placed under general
endotracheal anesthesia, at which time a right internal jugular
Swan-Ganz catheter and a left radial arterial line were placed.
Transesophageal echocardiography was performed, revealing severe AI,
moderate mitral regurgitation and severe dilatation of the aortic root
with dissection flaps.
At this time, the patient was prepped and draped
in the usual sterile fashion. A needlestick was performed in the right
common femoral artery followed by a guidewire placed up this and, via
Seldinger technique, changed out to an 8-French sheath. A Bentson wire
was placed up through the aorta under fluoroscopy and intravascular
ultrasound was used to visualize the wire. Clearly, the wire was in the
false lumen. After some manipulation, we were unable to go into the
true lumen and we did at that time turn our attention to the left leg.
A needlestick was performed and this was switched over with Seldinger to
an 8-French sheath followed by a Bentson wire and again intravascular
ultrasound was performed, revealing we were, indeed, in the true lumen.
At this time, that being in place, we did secure the extra stiff
Amplatzer wire in the true lumen and turned our attention back to the
patient's chest. An incision was made in the infraclavicular fossa on
the right-hand side. Dissection made with electrocautery down through
layers of the chest, splitting the pectoralis major muscles and, indeed,
opening the infraclavicular fossa and exposing the axillary artery. The
axillary artery was looped proximal and distally with Vesseloops.
A
midline sternotomy was then performed. Dissection made with
electrocautery down through the layers of the chest, exposing the
sternum, which was divided with a sternal saw, treated with Gelfoam, and
the pericardium was cleaned off of its fat. The patient was fully
heparinized. After the heparin had a chance to circulate, the axillary
artery was clamped proximal and distally, opened with an 11 blade,
extended with scissors, and matched to the proximal end of a 10
Hemashield graft, which was sewn with 5-0 Prolene. After this was
accomplished, Bioglue was placed on it. It was cannulated with a 7
Sarns Soft-Flow cannula, hooked up to the cardiopulmonary bypass circuit
without air. It is important to mention that even though we were
heparinized now, prior to heparinization, 2 whole units of the patient's
blood were drawn off to be given back to the patient at the end of the
case.
The pericardium was opened and there was an inflammatory aneurysm
in the ascending aorta, at least 8 cm in diameter, going down into the
root. Extensive dissection was performed around the aorta. A
pursestring was placed into the right atrium. This was cannulated with
a 3-stage venous cannula, hooked up to the cardiopulmonary bypass
circuit without air. Another pursestring was placed in the right
atrium, which was cannulated with a retrograde cardioplegia circuit.
Another pursestring was placed in the right superior pulmonary vein,
which was cannulated with an LV vent.
At this time, we did proceed with
cardiopulmonary bypass and began cooling the patient intensely. The
patient was cooled all the way down to 18 degrees centigrade as a goal.
At this time, we did turn our attention to the ascending aorta. With
the great size of the ascending aorta, a large cross-clamp was placed
around the aorta as well as the pulmonary artery and clamped and we did
arrest with retrograde cold blood cardioplegia. The ascending aorta was
opened widely and we could clearly visualize very large destroyed
dissection flaps. Hand-held cardioplegia was used to give antegrade
cold blood cardioplegia down the right coronary ostia. However, a total
of 1200 was given at the beginning. For the remainder of the case, an
additional 300 mL was given retrograde every 20-25 minutes. This was
done with the patient having clear blood coming back from the right and
left coronary ostia. Extensive dissection was performed, dissecting out
the entire root and the ascending aorta below the clamp. The root was
dissected down to the annulus exteriorly.
The valve appeared to have
good valvular tissue, but be a bicuspid valve. Therefore, I chose to
spare it at this time. Fourteen interrupted subvalvular sutures were
placed with pledgets. After this was accomplished, a 34 graft was
brought onto the field. The outflow tract was sized to a 25.
Therefore, a 34 graft was chosen. The 14 sutures were brought up
through the bottom of the graft, the graft was dropped into position.
The Hagar dilator was placed down the left outflow tract again and all
the sutures were tied, starting with the commissures and then running
around.
At this time, the patient reached 18 degrees centigrade. We
did tip in steep Trendelenburg position and proceeded with deep
hypothermic circulatory arrest. It is important to mention the patient
had already received a gram of Solu-Medrol and high dose of propofol to
provide burst suppression. Once on deep hypothermic circulatory arrest,
the ascending aorta was completely resected as well as the lesser
curvature of the arch and the ascending aorta was resected all the way
up to the innominate artery. The proximal transverse arch was also
removed completely. The true lumen clearly had the guidewire in, which
I had left. The true and false lumen were reapproximated with Teflon
felt provided as a neomedia. Running Vicryl was used to reapproximate
those 2 layers. Bioglue was placed on the 2 layers. After that was
accomplished, the guidewire was pulled forth. A 15 cm x 31 mm Gore Tag
graft was placed over the guidewire and put down the descending aorta in
an antegrade fashion. After this was accomplished, it was found to be
past the subclavian. It was deployed. After it was deployed, multiple
tacking sutures were used to secure it to the aorta so that it would not
slide or "bird's beak." After this was accomplished, the 28 sidearm
Hemashield graft was cut to size, brought onto the field and sewn to the
arch. After that was accomplished, the graft on the axillary artery was
clamped and the cannula was removed, cannulated into the side arm and
secured of the ascending graft. We had to de-air the patient at that
time, replace the crossclamp and proceed with cardiopulmonary bypass and
rewarming. The total deep hypothermic circulatory arrest time from
18 degrees centigrade was 27 minutes and the patient's cranial
saturations never dropped below 57 percent.
That being the case, I did
turn my attention back to the root. The commissures were secured to the
graft with pledgeted RB Prolenes. The valve was truly bicuspidized.
Trussler stitches were placed in the edges of the fused right and left
cusps to shorten it and make it the same length as the noncoronary cusp.
There was good approximation at this time and the valve was tested for
competency with cold saline and was found to be competent. At this
time, I did proceed to take a stitch and run it along the inside of the
graft, securing the edges of the aorta with the valve back to the
Hemashield graft. After this was accomplished, 2 coronary ostia holes
were cut in the Hemashield graft and the coronary buttons were cut out
circumferentially and sewn to the graft with 5-0 Prolene. This was all
reinforced with Bioglue. After that was accomplished, the 34 graft was
cut off at the level of the sinotubular junction, just above the
commissures, the distal graft was cut to length and the distal and
proximal grafts were anastomosed with running 4-0 Prolene. After this
was accomplished, ophthalmic cautery was used to make a small hole in
the ascending graft and an ascending vent was placed.
After this was
accomplished, we did give the patient warm blood cardioplegia. During 2
minutes of warm blood cardioplegia, 2 right ventricular and 2 right
atrial pacing wires were placed. The patient began beating. Once the
patient began beating, the patient was put into steep Trendelenburg
position again. The vents were turned on high, the cross-clamp was
removed in a low flow state and the flow state was brought back up.
After this was accomplished, we began ventilating. After ventilating
some time, we did load the patient's ventricle and check the function of
the aortic valve. The aortic valve was completely competent with no
evidence of regurgitation or stenosis. At this time, also the mitral
valve improved greatly with its very trivial mitral regurgitation. At
this time, we did remove the LV vent, tie down its pursestring, and
again view the valves, finding them in good condition, just as described
earlier. With the patient completely de-aired, we removed the ascending
vent, tied down its hole with a pursestring and another pledgeted
Prolene. With the vent out, the patient ventilating, warm and in normal
sinus rhythm, we were able to wean from cardiopulmonary bypass.
At this
time, we weaned from cardiopulmonary bypass, removed the retrograde
cardioplegic cannula, tied down its pursestring, removed the venous
cannula, tied down its pursestring. The patient still hemodynamically
stable, we reversed the patient's heparinization with protamine. At
this time, we gave the patient back all his blood from the pump. The
patient still hemodynamically stable, we did tie off the sidearm grafts
and then cut them off. After this was accomplished, with the patient
hemodynamically stable, we did use multiple topical hemostatic agents,
including Gelfoam thrombin and Arista. With good surgical hemostasis
and the patient hemodynamically stable, we also gave DDAVP. That being
completed, with a good thromboelastogram, we gave the patient back his
own blood. The patient was hemostatic and hemodynamically stable.
We
did proceed with closure. Two Blake drains were placed, one behind the
heart and one in front of the heart. The pericardium was closed with
running Vicryl. Four interrupted figure-of-eight Pioneer cables were
placed across the sternum. The underside of the sternum was reinspected
and found to be hemostatic. The sternum was treated with vancomycin,
Gelfoam, and thrombin paste. The sternum was reapproximated. The
cables were tightened, clipped, and cut. The patient was washed out
with antibiotic saline. We did at that time close the fascia with
running Vicryl. We washed him out again. The subcutaneous tissue was
closed with running Vicryl. Skin was closed with running Vicryl
subcuticular stitch followed by LiquiBand. Attention turned to the
axilla. The graft was tied off and cut low. With good surgical
hemostasis, the pectoralis was reapproximated with running Vicryl.
Subcutaneous tissue was reapproximated with running Vicryl. Skin was
closed with running Vicryl subcuticular stitch followed by LiquiBand.
The right groin line was removed. Pressure was held for 15 minutes and
the groin was stable with good pulses in the feet. At this time, we did
have instrument, sponge, and needle counts correct, did return the
patient to the CCU, intubated, in stable condition, on no drips and
having received no blood products.
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5 comments:
Have you ever had Alaskan Pale Ale?
: )
For sure, and Alaskan Brewing might have been here at the fest with some taps. But most of the brewers here are much smaller and more local than AB - you won't find many of these beers outside of the local pubs.
I like how you went from a 'white male' to a 'gentleman'. see you two soon! xx r
I kept telling them to call me dude!
New definition for living Aloha: "This is a tanned and healthy-appearing 53-year-old gentleman in no distress at rest."
Thanks for sharing the details ... incredibly complex and invasive. Yikes !! But your experience is clearly improving the right side of the odds !!
Adu ...
-- Nat
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